(CNN)The world could soon have another vaccine option in its fight against Covid-19.
European drug makers Sanofi and GSK announced positive results from late-stage clinical testing of a new vaccine that will be named Vidprevtyn, according to a Sanofi spokesperson. The companies plan to seek authorization for the shots in the US and Europe.
Sanofi-GSK COVID-19 Vaccine (Vidprevtyn) For 2022
The Sanofi-GSK codeveloped (Vidprevtyn) (VAT00002, VAT00008) protein-based vaccine candidate combines innovative technologies to produce an adjuvanted recombinant protein-based COVID-19 vaccine. Combining a protein-based antigen and an adjuvant is a well-established technology and is used in several vaccines.
Sanofi Pasteur is contributing its S-protein COVID-19 antigen based on recombinant DNA technology. This technology has produced an exact genetic match to proteins found on the surface of the SARS-CoV-2 coronavirus. In addition, the DNA sequence encoding this antigen has been combined into the baculovirus expression platform’s DNA, based on Sanofi’s licensed recombinant influenza Flublok product in the USA
What is Recombinant DNA technology?
Recombinant DNA (rDNA) is a technology that uses enzymes to cut and paste together DNA sequences of interest. The recombined DNA sequences can be placed into vehicles called vectors that ferry the DNA into a suitable host cell where it can be copied or expressed.
Pieces of DNA, such as human DNA, can be engineered in a fashion that allows them to be copied, or replicated, in bacteria or yeast. This involves attaching appropriate elements to a piece of DNA and then transferring into a bacterial or yeast cell, with those elements then instructing the bacterial or yeast cell to copy this DNA along with its own. This process is known as DNA cloning, with the resulting cloned DNA often referred to as recombinant DNA.
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