CDC: Bacterium that causes rare disease likely endemic along Gulf Coast (MOB Adverse Event!!)

Melioidosis has a wide range of signs and symptoms. It can be mistaken for other diseases, such as tuberculosis or more common forms of pneumonia.
Mortality rate was 25.9% with 16.5% attributable to melioidosis. Most (65.9%) deaths occurred early during the initial hospitalisation, with a median time to death of 6 days.

Disease detectives investigating a pair of medical mysteries in Mississippi have come to an unwelcome conclusion. The bacterium that causes a rare but dangerous disease called melioidosis is likely endemic in parts of the southern United States, along the Gulf Coast.

The bacterium, Burkholderia pseudomallei, was previously not thought to be found in the U.S., meaning people who had symptoms similar to those of melioidosis but who had no history of international travel were considered unlikely to be infected with it. That assumption is no longer sound — or safe, said experts at the Centers for Disease Control and Prevention, which on Wednesday issued a health alert to physicians.

“This is a big deal because clinicians generally speaking only consider melioidosis in patients who have recent travel to an endemic area like Thailand, South Asia, Australia. They would not consider just somebody living in the Gulf Coast area who has never traveled, that they would have melioidosis,” Julia Petras, an epidemic intelligence service officer with CDC’s bacterial special pathogens branch, told STAT.

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