Monkeypox: FDA expands vaccine supply, allows shots for children/Polio vaccine boosters are offered to London children as the virus spreads

LONDON — Children ages 1-9 in London were made eligible for booster doses of a polio vaccine Wednesday after British health authorities reported finding evidence the virus has spread in multiple areas of the city but found no cases of the paralytic disease in people.

The Food and Drug Administration on Tuesday expanded its authorization for the monkeypox vaccine in a way that would significantly boost the limited supply of shots.

The FDA is also now allowing children to receive the vaccine if they are at high risk of monkeypox infection. Dr. Peter Marks, head of the FDA’s vaccine division, said there has been an increase in possible exposures among children over the past week.

Health-care providers can now administer the shots to adults through intradermal injection, or between the layers of the skin. This will increase the supply of doses by as much as fivefold, according to the FDA. The vaccine is traditionally administered through subcutaneous injection, which goes into the fat layer beneath the skin.

The intradermal injections for adults use a lower volume dosage that will allow 400,000 vials in the strategic national stockpile to provide up to 2 million shots, according to Robert Fenton, the White House monkeypox response coordinator.

Children will receive the vaccine through the typical subcutaneous injection. Marks said there isn’t enough data to allow intradermal injections for kids and this method is also difficult to administer to very young children.

Jynneos is the only FDA-approved monkeypox vaccine in the U.S. The shots are administered in two doses 28 days apart. Jynneos is manufactured by Bavarian Nordic, a biotech company based in Denmark.

As monkeypox cases emerge in US and Europe, Bavarian Nordic inks vaccine order | Fierce Pharma (MVA – Gene Editing)

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